HPLC2GS is a binary gradient system with two parallel pumps, enabling gradient elution — the controlled variation of mobile phase composition over time — making it suitable for complex sample matrices and multi-component separations.Software compliance with GLP and FDA-21 CFR Part 11 requirements makes these systems suitable for regulated pharmaceutical and quality-control environments.

Salient Features

Pump System

1. Isocratic & Gradient (Binary) Configurations — HPLC1IS offers single-pump isocratic operation for routine analysis; HPLC2GS uses two in-parallel pumps for binary gradient elution, enabling complex separations with changing mobile phase ratios.
2. Superior High-Pressure Pump — Dual-plunger in-series design with floating plunger technology ensures accurate, stable solvent delivery with minimal pulsation. Single stroke discharged fluid volume of 30 µL.
3. Low Flow Pulsation — Electronic Pressure Control (EPC) technology actively suppresses flow pulsation, ensuring minimum baseline noise and stable detector signals throughout the run.
4. High Flow Accuracy & Repeatability — Multi-point flow calibration curve ensures ±0.5% flow accuracy across the full 0.001–9.999 ml/min range, with RSD ≤ 0.1% flow precision.
5. Long Seal Life — Floating plunger design minimises lateral stress on the high-pressure seal, significantly extending its service life and reducing maintenance frequency.
6. HPLC2GS Parallel Pump Operation — The two pumps work in parallel and in perfect synchronisation, ensuring gradient accuracy, long-term durability, and consistent solvent blending ratios.

UV Detector

7. Broad Wavelength Range — Standard detection range of 190–400 nm with optional extension to 700 nm, covering UV and visible spectrum for a wide range of analytes.
8. Dual Wavelength Detection (HPLC2GS) — Dual optical path system enables simultaneous dual-wavelength detection, improving peak identification and quantification in complex samples.
9. High-Precision Stepper-Controlled Monochromator — Imported high-precision stepper motor control improves wavelength accuracy to ±1 nm, with wavelength precision of ±0.1 nm.
10. Wavelength Automatic Correction — New automatic wavelength calibration method compensates for lamp ageing and environmental drift, maintaining long-term accuracy without manual recalibration.
11. Multi-Mode Wavelength Scanning — Three scanning modes with fully programmable wavelength settings, enabling flexible method development across different detection requirements.

Interface & Software

1. 12. OLED Graphic Display — Clear, high-contrast OLED display on both pump and detector modules for intuitive parameter monitoring and control.
   13. Dual Control Modes — Operates via instrument panel control or computer remote control, with 10 user-programmable methods supporting flow and gradient programming.
   14. Electronic Signature Function — Built-in electronic signature capability supports audit trail documentation and user accountability in regulated environments.
   15. GLP / FDA-21 CFR Part 11 Compliant Software — Full compatibility with Good Laboratory Practice and FDA electronic records and signatures regulations, making the system audit-ready for pharmaceutical QC labs.
   16. Injector: 7725i 6-Port Valve — Industry-standard Rheodyne 7725i 6-port injection valve for reliable, reproducible sample introduction with minimal dead volume.

📊 Specifications Table

🔍 Detector Specifications (UV Detector)